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Lumefantrine Impurity B & C Mixture

Lumefantrine Impurity B & C Mixture

Product Description
CAT No.
ALN-L058017
CAS No.
NA
Mol. F.
C44H24Cl6O2 : C44H24Cl6O2
Mol. Wt.
797.4 : 797.4
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Chemical Name : 1,4-bis(2,7-dichloro-9-((Z)-4-chlorobenzylidene)-9H-fluoren-4-yl)-3,6-dioxabicyclo[3.1.0]hexane compound with 2,3′-bis(2,7-dichloro-9-((Z)-4-chlorobenzylidene)-9H-fluoren-4-yl)-2,2′-bioxirane (1:1)
Smiles : ClC1=CC(C2(COC3C4=C(C5=CC=C(Cl)C=C5/C6=C/C7=CC=C(Cl)C=C7)C6=CC(Cl)=C4)C3O2)=C(C8=CC=C(Cl)C=C/98)C(C9=C/C%10=CC=C(Cl)C=C%10)=C1.ClC%11=CC(C%12(C%13C(C%14=C(C%15=CC=C(Cl)C=C%15/C%16=C/C%17=CC=C(Cl)C=C%17)C%16=CC(Cl)=C%14)O%13)CO%12)=C(C%18=CC=C(Cl)C=C/%19%18)C(C%19=C/C%20=CC=C(Cl)C=C%20)=C%11
Inchi : InChI=1S/C27H36F2O5/c1-5-6-7-21(33)34-13-20(32)22-14(2)10-16-15-11-17(28)24-25(29)18(30)8-9-26(24,3)23(15)19(31)12-27(16,22)4/h8-9,14-17,19,22-23,31H,5-7,10-13H2,1-4H3/t14-,15+,16+,17-,19+,22-,23-,26-,27+/m1/s1

Stability-indicating HPLC-DAD/UV-ESI/MS impurity profiling of the anti-malarial drug lumefantrine

Mathieu Verbeken1u2020 , Sultan Suleman1,3u2020 , Bram Baert1 , Elien Vangheluwe1 , Sylvia Van Dorpe1 , Christian Burvenich2 , Luc Duchateau2 , Frans H Jansen4 , Bart De SpiegeleernVerbeken et al. Malaria Journal 2011, 10:51 Page 2 of 9

Analytical Method Development and Validation for Estimation of Lumifantrine in Pharmaceutical Dosage Forms by HPLC

Naveen S Kotur

A Modified Method for Determination of Lumefantrine in Human Plasma by HPLC-UV and Combination of Protein Precipitation and Solid-Phase Extraction: Application to a Pharmacokinetic Study

1 ,Singaravel Sivasamy2 , S.Srinivasan – J. Pharm. Sci. & Res. Vol.4(1), 2012,1672-1675

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