Methotrexate Dimethylamide

Product Description
CAT No.
ALN-M019019
CAS No.
71074-44-7
Mol. F.
C22H27N9O4
Mol. Wt.
481.5
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Technical Data
Reference
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Product Overview
Chemical Name : N2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-N5,N5-dimethyl-L-glutamine
Smiles : NC1=NC(N)=NC2=NC=C(CN(C3=CC=C(C(N[C@H](C(O)=O)CCC(N(C)C)=O)=O)C=C3)C)N=C12
Inchi : InChI=1S/C17H25N3O2S/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14/h3-4,11-12,14,18-19H,5-10H2,1-2H3/i2D3
Technical Data
Reference
Identification and Quantitation of Impurities in Methotrexate
dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624
determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection
mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140
Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391
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