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Methotrexate EP Impurity D

Methotrexate EP Impurity D

Product Description
CAT No.
ALN-M019005
CAS No.
5623-18-7
Mol. F.
C15H14N6O3
Mol. Wt.
326.3
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RFQ
Chemical Name : 4-(((2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl)(methyl)amino)benzoic acid
Smiles : NC(NC1=C2N=C(CN(C)C3=CC=C(C(O)=O)C=C3)C=N1)=NC2=O
Inchi : InChI=1S/C26H30N6O9/c1-32-21-20(23(37)31-26(32)27)15(12-28-21)7-4-13-2-5-14(6-3-13)22(36)30-17(25(40)41)8-10-18(33)29-16(24(38)39)9-11-19(34)35/h2-3,5-6,12,16-17,28H,4,7-11H2,1H3,(H,29,33)(H,30,36)(H,34,35)(H,38,39)(H,40,41)(H2,27,31,37)/t16-,17-/m0/s1

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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