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Methotrexate EP Impurity E

Methotrexate EP Impurity E

Product Description
CAT No.
ALN-M019006
CAS No.
19741-14-1
Mol. F.
C15H15N7O2
Mol. Wt.
325.3
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RFQ
Chemical Name : 4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoic acid
Smiles : NC1=NC(N=CC(CN(C)C2=CC=C(C(O)=O)C=C2)=N3)=C3C(N)=N1
Inchi : InChI=1S/C20H21N7O6/c1-27(9-11-8-22-16-15(23-11)18(31)26-20(21)25-16)12-4-2-10(3-5-12)17(30)24-13(19(32)33)6-7-14(28)29/h2-5,8,13H,6-7,9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H3,21,22,25,26,31)/t13-/m0/s1

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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