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Methotrexate EP Impurity F

Methotrexate EP Impurity F

Product Description
CAT No.
ALN-M019007
CAS No.
51865-79-3
Mol. F.
C20H22N8O5
Mol. Wt.
454.4
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RFQ
Chemical Name : (2R)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl] amino] pentanedioic acid
Smiles : NC1=NC(N)=C2C(N=CC(CN(C)C3=CC=C(C(N[C@@]([H])(C(O)=O)CCC(O)=O)=O)C=C3)=N2)=N1
Inchi : InChI=1S/C15H15N7O2/c1-22(10-4-2-8(3-5-10)14(23)24)7-9-6-18-13-11(19-9)12(16)20-15(17)21-13/h2-6H,7H2,1H3,(H,23,24)(H4,16,17,18,20,21)
Synonym : Earlier CAT No = ALN-M019017

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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