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Methotrexate EP Impurity G

Methotrexate EP Impurity G

Product Description
CAT No.
ALN-M019008
CAS No.
2519848-42-9
Mol. F.
C28H29N9O6
Mol. Wt.
587.6
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RFQ
Chemical Name : (4-(4-(((2,4-diamino-4a,8a-dihydropteridin-6-yl)methyl)(methyl)amino)-N-methylbenzamido)benzoyl)-L-glutamic acid
Smiles : NC1=NC(N=CC(CN(C)C2=CC=C(C(N(C3=CC=C(C(N[C@@](CCC(O)=O)(C(O)=O)[H])=O)C=C3)C)=O)C=C2)=N4)=C4C(N)=N1
Inchi : InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m1/s1

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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