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Methotrexate Impurity 1

Methotrexate Impurity 1

Product Description
CAT No.
ALN-M019024
CAS No.
1029980-84-4
Mol. F.
C17H24N2O5
Mol. Wt.
336.4
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RFQ
Chemical Name : Diethyl N-(2-Methylaminobenzoyl)-L-glutamate ; Diethyl (2S)-2-{[2-(methylamino)benzoyl]amino}pentanedioate
Smiles : O=C(OCC)[C@@H](NC(C1=CC=CC=C1NC)=O)CCC(OCC)=O
Inchi : InChI=1S/C17H15BrO4/c1-21-17(20)14-9-13(15(19)10-18)7-8-16(14)22-11-12-5-3-2-4-6-12/h2-9H,10-11H2,1H3

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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