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Methotrexate Impurity 2

Methotrexate Impurity 2

Product Description
CAT No.
ALN-M019025
CAS No.
51865-66-8
Mol. F.
C17H24N2O5
Mol. Wt.
336.4
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Chemical Name : Diethyl (4-(methylamino)benzoyl)-D-glutamate
Smiles : O=C(OCC)CC[C@H](C(OCC)=O)NC(C1=CC=C(NC)C=C1)=O
Inchi : InChI=1S/C17H24N2O5/c1-4-23-15(20)11-10-14(17(22)24-5-2)19-16(21)12-8-6-7-9-13(12)18-3/h6-9,14,18H,4-5,10-11H2,1-3H3,(H,19,21)/t14-/m0/s1

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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