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N-Nitroso Methotrexate EP Impurity-B

N-Nitroso Methotrexate EP Impurity-B

Product Description
CAT No.
ALN-M019028
CAS No.
NA
Mol. F.
C19H19N9O6
Mol. Wt.
469.4
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RFQ
Chemical Name : (4-(((2,4-Diaminopteridin-6-yl)methyl)(nitroso)amino)benzoyl)-L-glutamic acid
Smiles : NC1=NC(N)=C2C(N=CC(CN(N=O)C3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)=N2)=N1
Inchi : InChI=1S/C22H24N8O10/c31-11-9-27(23-37)5-7-29(25-39)13-1-2-14(30(26-40)8-6-28(24-38)10-12-32)18-17(13)21(35)19-15(33)3-4-16(34)20(19)22(18)36/h1-4,31-34H,5-12H2

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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