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N-Nitroso Methotrexate EP Impurity-L

N-Nitroso Methotrexate EP Impurity-L

Product Description
CAT No.
ALN-M019029
CAS No.
NA
Mol. F.
C13H15N3O6
Mol. Wt.
309.3
Stock
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RFQ
Chemical Name : (4-(Methyl(nitroso)amino)benzoyl)-L-glutamic acid
Smiles : O=C(N[C@H](C(O)=O)CCC(O)=O)C1=CC=C(N(C)N=O)C=C1
Inchi : InChI=1S/C19H19N9O6/c20-15-14-16(26-19(21)25-15)22-7-10(23-14)8-28(27-34)11-3-1-9(2-4-11)17(31)24-12(18(32)33)5-6-13(29)30/h1-4,7,12H,5-6,8H2,(H,24,31)(H,29,30)(H,32,33)(H4,20,21,22,25,26)/t12-/m0/s1

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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