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N-Nitroso Methotrexate EP Impurity L

N-Nitroso Methotrexate EP Impurity L

Product Description
CAT No.
ALN-M019032
CAS No.
NA
Mol. F.
C13H15N3O6
Mol. Wt.
309.3
Stock
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RFQ
Chemical Name : N-(4-(methylamino)benzoyl)-N-nitroso-L-glutamic acid
Smiles : CNC1=CC=C(C(N([C@@H](CCC(O)=O)C(O)=O)N=O)=O)C=C1
Inchi : InChI=1S/C21H23N9O6.2Na/c1-21(19(34)35,8-7-14(31)32)30(28-36)18(33)11-3-5-13(6-4-11)29(2)10-12-9-24-17-15(25-12)16(22)26-20(23)27-17;;/h3-6,9H,7-8,10H2,1-2H3,(H,31,32)(H,34,35)(H4,22,23,24,26,27);;/q;2*+1/p-2/t21-;;/m0../s1

Identification and Quantitation of Impurities in Methotrexate

dulal c. chatterji, altice g. frazier, and joseph f. gallellnJournal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection

mark c. roach, philippe gozel and richard n. zare – Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples

Forough Karami , Sara Ranjbar\xa0 , Younes Ghasemi , Manica Negahdaripour – Journal of Pharmaceutical Analysis 9 (2019) 373-391

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