Nadolol EP Impurity F
Product Description
CAT No.
ALN-N002007
CAS No.
2116-22-5
Mol. F.
C17H23NO2
Mol. Wt.
273.4
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : (2RS)-1-[(1,1-Dimethylethyl)amino]-3-(naphthalen-1-yloxy)propan-2-ol (as per EP)
Smiles : OC(CNC(C)(C)C)COC1=CC=CC2=C1C=CC=C2
Inchi : InChI=1S/C17H26INO4/c1-17(2,3)19-8-10(20)9-23-16-5-4-13(18)11-6-14(21)15(22)7-12(11)16/h4-5,10,14-15,19-22H,6-9H2,1-3H3/t10?,14-,15+/m0/s1
Synonym : Nadolol USP Related Compound F
Technical Data
Reference
Nadolol: high-pressure liquid chromatographic methods for assay, racemate composition and related compounds
pauline m. lacroix,t norman m. curran and edward g. loveringnJournal of Pharmaceutical & Biomedical Analysis Vol. 10, Nos 10-12, pp. 917-924, 1992
The nonmetabolized u03b2u2011blocker nadolol is a substrate of oct1, oct2, mate1, mate2-k, and pu2011glycoprotein, but not of oatp1b1 and oatp1b3
Shingen Misaka, Jana Knop, Katrin Singer, Eva Hoier, Markus Keiser, Fabian Mu?ller, Hartmut Glaeser, Jo? rg Ko? nig, and Martin F. Fromm – Mol. Pharmaceutics 2016, 13, 2, 512–519
Separation of nadolol racemates by high pH reversed-phase preparative chromatography
Rami S. Arafaha,b , António E. Ribeiroa,b , Alírio E. Rodriguesc , Luís S. Pais – Separation and Purification Technology Volume 233, 15 February 2020, 116018
RFQ
