Nadolol Epoxide Impurity

Product Description
CAT No.
ALN-N002013
CAS No.
35697-15-5
Mol. F.
C13H16O4
Mol. Wt.
236.3
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 5-(Oxiran-2-ylmethoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol
Smiles : OC1C(O)CC2=CC=CC(OCC3CO3)=C2C1
Inchi : InChI=1/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2
Technical Data
Reference
Nadolol: high-pressure liquid chromatographic methods for assay, racemate composition and related compounds
pauline m. lacroix,t norman m. curran and edward g. loveringnJournal of Pharmaceutical & Biomedical Analysis Vol. 10, Nos 10-12, pp. 917-924, 1992
The nonmetabolized u03b2u2011blocker nadolol is a substrate of oct1, oct2, mate1, mate2-k, and pu2011glycoprotein, but not of oatp1b1 and oatp1b3
Shingen Misaka, Jana Knop, Katrin Singer, Eva Hoier, Markus Keiser, Fabian Mu?ller, Hartmut Glaeser, Jo? rg Ko? nig, and Martin F. Fromm – Mol. Pharmaceutics 2016, 13, 2, 512–519
Separation of nadolol racemates by high pH reversed-phase preparative chromatography
Rami S. Arafaha,b , António E. Ribeiroa,b , Alírio E. Rodriguesc , Luís S. Pais – Separation and Purification Technology Volume 233, 15 February 2020, 116018
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