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N-Nitroso N-Desbenzyl Nicardipine Impurity

N-Nitroso N-Desbenzyl Nicardipine Impurity

Product Description
CAT No.
ALN-N004027
CAS No.
NA
Mol. F.
C19H22N4O7
Mol. Wt.
418.4
Stock
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RFQ
Chemical Name : 3-Methyl 5-(2-(methyl(nitroso)amino)ethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
Smiles : CC1=C(C(OCCN(C)N=O)=O)C(C(C(OC)=O)=C(C)N1)C2=CC([N+]([O-])=O)=CC=C2
Inchi : InChI=1S/C11H9NO/c13-11-8-4-5-9-12(11)10-6-2-1-3-7-10/h1-9H

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS

Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance

M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC

C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

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