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Nicardipine Cyclohexenone Impurity

Nicardipine Cyclohexenone Impurity

Product Description
CAT No.
ALN-N004006
CAS No.
87625-92-1
Mol. F.
C15H15NO5
Mol. Wt.
289.3
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RFQ
Chemical Name : 2-​Cyclohexene-​1-​carboxylic acid, 2-​methyl-​6-​(3-​nitrophenyl)​-​4-​oxo-​, methyl ester; Methyl 2-methyl-6-(3-nitrophenyl)-4-oxo-2-cyclohexene-1-carboxylate;
Smiles : O=C(C1C(C)=CC(CC1C2=CC=CC([N+]([O-])=O)=C2)=O)OC
Inchi : InChI=1S/C7H5NO4/c9-6(10)4-1-5(7(11)12)3-8-2-4/h1-3H,(H,9,10)(H,11,12)
Synonym : Nicardipine Impurity A

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS

Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance

M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC

C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

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