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Nicardipine Impurity 1

Nicardipine Impurity 1

Product Description
CAT No.
ALN-N004011
CAS No.
10323-98-5
Mol. F.
C13H13NO3
Mol. Wt.
231.3
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Chemical Name : 3-Methyl-5-(3-nitrophenyl)cyclohex-2-enone ; 3-Methyl-5-(m-nitrophenyl)-2-cyclohexen-1-one
Smiles : O=C(C1)C=C(C)CC1C2=CC([N+]([O-])=O)=CC=C2
Inchi : InChI=1S/C39H47NO4/c41-31-37-28-36(23-24-39(37)44-32-35-21-10-5-11-22-35)38(42)30-40(29-34-19-8-4-9-20-34)25-13-1-2-14-26-43-27-15-12-18-33-16-6-3-7-17-33/h3-11,16-17,19-24,28,41H,1-2,12-15,18,25-27,29-32H2

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS

Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance

M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC

C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

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