Nicardipine Impurity 2

Product Description
CAT No.
ALN-N004012
CAS No.
2469735-68-8
Mol. F.
C15H15NO5
Mol. Wt.
289.3
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : Methyl 4-Methyl-6-(3-nitrophenyl)-2-oxo-cyclohex-3-enyl Carboxylate
Smiles : O=C(C1C(OC)=O)C=C(C)CC1C2=CC([N+]([O-])=O)=CC=C2
Inchi : InChI=1/C13H13NO3/c1-9-5-11(8-13(15)6-9)10-3-2-4-12(7-10)14(16)17/h2-4,6-7,11H,5,8H2,1H3
Technical Data
Reference
Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993
Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.
Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849
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