Nicardipine Impurity 5

Product Description
CAT No.
ALN-N004020
CAS No.
NA
Mol. F.
C26H28N2O7
Mol. Wt.
480.5
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Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : 2-(2-(Benzyl(methyl)amino)ethyl) 6-methyl 5-methyl-3′-nitro-3-oxo-1,2,3,6-tetrahydro-[1,1′-biphenyl]-2,6-dicarboxylate
Smiles : O=C(C(C(C1=CC=CC([N+]([O-])=O)=C1)C2C(OCCN(CC3=CC=CC=C3)C)=O)C(C)=CC2=O)OC
Inchi : InChI=1S/C30H33N7O9S/c38-30(34-47(43,44)24-2-4-26(27(17-24)36(40)41)32-18-20-6-13-45-14-7-20)25-3-1-22(37(42)11-9-35(39)10-12-37)16-28(25)46-23-15-21-5-8-31-29(21)33-19-23/h1-5,8,15-17,19-20,32,35H,6-7,9-14,18H2,(H,31,33)(H,34,38)
Technical Data
Reference
Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993
Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.
Chromatographic purity and assay of nicardipine by HPLC
C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849
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