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Nicardipine USP Related Compound A

Nicardipine USP Related Compound A

Product Description
CAT No.
ALN-N004002
CAS No.
74936-72-4
Mol. F.
C16H16N2O6
Mol. Wt.
332.3
Stock
In Stock
Chemical Name : 3,​5-​Pyridinedicarboxylic acid, 1,​4-​dihydro-​2,​6-​dimethyl-​4-​(3-​nitrophenyl)​-​, 3-​methyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, monomethyl ester (9CI); (±)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid monomethyl ester; (±)-1,4-Dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)-3-pyridinecarboxylic acid; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid monomethyl ester; 2,6-Dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylic acid;
Smiles : O=C(C(C(C1=CC([N](=O)=O)=CC=C1)C(C(O)=O)=C(C)N2)=C2C)OC
Inchi : InChI=1/C26H29N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15,24,27H,13-14,16H2,1-4H3;1H

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS

Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance

M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC

C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849

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