Nicardipine USP Related Compound C
 
		Product Description
CAT No.
				
									ALN-N004004								
				CAS No.
				
									21881-77-6								
				Mol. F.
				
									C17H18N2O6								
				Mol. Wt.
				
									346.3								
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							Product Overview
			
						
									Chemical Name : 3,​5-​Pyridinedicarboxylic acid, 1,​4-​dihydro-​2,​6-​dimethyl-​4-​(3-​nitrophenyl)​-​, 3,​5-​dimethyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, dimethyl ester (9CI); 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-, dimethyl ester (8CI)3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-, dimethyl ester (8CI); 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester; Dimethyl 4-(m-nitrophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate; m-Nifedipine;								
				
									Smiles : O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OC								
				
									Inchi : InChI=1S/C26H27N3O6.ClH/c1-17-22(25(30)34-4)24(20-11-8-12-21(15-20)29(32)33)23(18(2)27-17)26(31)35-14-13-28(3)16-19-9-6-5-7-10-19;/h5-12,15H,13-14,16H2,1-4H3;1H								
				
							
							
							Technical Data
			
						
							
							
							Reference
			
						Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS
									Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993								
				Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance
									M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20. 								
				Chromatographic purity and assay of nicardipine by HPLC
									C. V. Fernández\xa0 D. F. Mira\xa0 G. I. Luque – Journal of High Resolution Chromatography Volume13, Issue12 December 1990 Pages 846-849 								
				
							
							
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