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Nicardipine USP Related Compound D

Nicardipine USP Related Compound D

Product Description
CAT No.
ALN-N004008
CAS No.
71784-27-5
Mol. F.
C35H40N4O6 : 2(HCl)
Mol. Wt.
612.7 : 2(36.5)
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RFQ
Chemical Name : Bis(2-(benzyl(methyl)amino)ethyl) 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Dihydrochloride
Smiles : O=C(C1=C(C)NC(C)=C(C(OCCN(CC2=CC=CC=C2)C)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OCCN(CC4=CC=CC=C4)C.[2HCl]
Inchi : InChI=1S/C8H4Cl4O/c9-7(13)5-1-3-6(4-2-5)8(10,11)12/h1-4H
Synonym : Nicardipine Bis analog

Stability-indicating HPLC method for the determination of nicardipine in capsules and spiked human plasma. Identification of degradation products using HPLC/MS

Sheikha M.Al-Ghannam,Abeer M.Al-OlayannArabian Journal of Chemistry Volume 12, Issue 8, December 2019, Pages 1983-1993

Employing ionization behaviors to resolve a trace-level impurity: determination of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5- pyridinedicarboxylic acid di-2-[methyl-(phenylmethyl)amino]ethyl ester in nicardipine drug substance

M B Maurin 1, R D Vickery, P Ma, J Manalo, M A Hussain – Pharm Res. 1992 Nov;9(11):1518-20.

Chromatographic purity and assay of nicardipine by HPLC

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