Pazopanib-d3

Product Description
CAT No.
ALN-P013D01
CAS No.
1219591-97-5
Mol. F.
C21H20D3N7O2S
Mol. Wt.
440.5
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl-d3)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide
Smiles : CC1=C(S(=O)(N)=O)C=C(NC2=NC=CC(N(C([2H])([2H])[2H])C3=CC4=NN(C)C(C)=C4C=C3)=N2)C=C1
Inchi : InChI=1S/C28H38N4O3S/c33-27(24-18-9-10-19(15-18)25(24)28(34)35)29-16-20-5-1-2-6-21(20)17-31-11-13-32(14-12-31)26-22-7-3-4-8-23(22)36-30-26/h3-4,7-8,18-21,24-25H,1-2,5-6,9-17H2,(H,29,33)(H,34,35)/t18-,19+,20-,21-,24+,25-/m0/s1
Technical Data
Reference
Analytical control of process impurities in Pazopanib hydrochloride by impurity fate mapping
Yan Li 1, David Q Liu, Shawn Yang, Ravinder Sudini, Michael A McGuire, Dharmesh S Bhanushali, Alireza S KordnJ Pharm Biomed Anal. 2010 Aug 1;52(4):493-507.
Determination and characterization of process impurities in pazopanib hydrochloride drug substance
musty sharada, ravichandra babu – Int J Pharm Pharm Sci, Vol 8, Issue 4, 97-102
Characterization of forced degradation products of pazopanib hydrochloride by UHPLC?Q?TOF/MS and in silico toxicity prediction
Prinesh N. Patel\xa0 Pradipbhai D. Kalariya\xa0 Mahesh Sharma\xa0 Prabha Garg\xa0 M. V. N Kumar Talluri\xa0 S. Gananadhamu\xa0 R. Srinivas – Journal of mass spectrometry Volume50, Issue7 July 2015 Pages 918-928
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