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Pemetrexed EP Impurity E

Pemetrexed EP Impurity E

Product Description
CAT No.
ALN-P014006
CAS No.
182009-04-7
Mol. F.
C20H21N5O6
Mol. Wt.
427.4
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Chemical Name : (2R)-2-[4-[2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzamido]pentanedioic acid (as per EP)
Smiles : O=C(O)[C@H](NC(C1=CC=C(CCC2=CNC(NC(N)=N3)=C2C3=O)C=C1)=O)CCC(O)=O
Inchi : InChI=1S/C24H21ClFN3O5/c1-24(26)19(34-21(31)16-10-6-3-7-11-16)17(14-25)33-22(24)29-13-12-18(28-23(29)32)27-20(30)15-8-4-2-5-9-15/h2-13,17,19,22H,14H2,1H3,(H,27,28,30,32)/t17-,19-,22-,24-/m1/s1
Synonym : Pemetrexed R-Isomer

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A new validated stability-indicating gradient RP-HPLC method for the determination of pemetrexed disodium and its process related substances

By Hemchand, S.; Babu, R. Ravi Chandra; Annapurna, Mukthinuthalapati Mathrusri – From Journal of Drug Delivery and Therapeutics (2019), 9(3Suppl.), 588-610

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