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Pemetrexed Impurity 20

Pemetrexed Impurity 20

Product Description
CAT No.
ALN-P014015
CAS No.
NA
Mol. F.
C25H28N6O9
Mol. Wt.
556.5
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Chemical Name : (4-(2-(2-((S)-4-Amino-4-carboxybutanamido)-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzoyl)-L-glutamic acid
Smiles : O=C1C2=C(NC=C2CCC3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)NC(NC(CC[C@@H](C(O)=O)N)=O)=N1
Inchi : InChI=1S/C19H21N5O7/c20-15-14(17(29)24-19(21)23-15)12(25)7-3-9-1-4-10(5-2-9)16(28)22-11(18(30)31)6-8-13(26)27/h1-2,4-5,11H,3,6-8H2,(H,22,28)(H,26,27)(H,30,31)(H5,20,21,23,24,29)/t11-/m0/s1

A stability-indicating LC-MS/MS method optimization for Pemetrexed through design of experiments: Identification and characterization of major oxidative degradation product

By Narenderan, S. T.; Ramesh, J.; Babu, B.; Meyyanathan, S. N.nFrom Journal of Pharmaceutical and Biomedical Analysis (2020), 183, 113150

A new validated stability-indicating gradient RP-HPLC method for the determination of pemetrexed disodium and its process related substances

By Hemchand, S.; Babu, R. Ravi Chandra; Annapurna, Mukthinuthalapati Mathrusri – From Journal of Drug Delivery and Therapeutics (2019), 9(3Suppl.), 588-610

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