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Pyrimethamine BP Impurity 3

Pyrimethamine BP Impurity 3

Product Description
CAT No.
ALN-P068007
CAS No.
93456-61-2
Mol. F.
C12H12ClN3O
Mol. Wt.
249.7
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RFQ
Chemical Name : 4-amino-5-(4-chlorophenyl)-6-ethyl-1,2-dihydropyrimidin-2-one
Smiles : O=C1N=C(N)C(C2=CC=C(Cl)C=C2)=C(CC)N1
Inchi : InChI=1S/C12H11ClN2O2/c1-2-9-10(11(16)15-12(17)14-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H2,14,15,16,17)

Development of a simple, rapid, and robust liquid chromatographic method for the simultaneous determination of sulfalene, sulfadoxine, and pyrimethamine in tablets

Yonah H.Mwalwisi, Ludwig Hoellein, Eliangiringa Kaale, UlrikeHolzgrabenJournal of Pharmaceutical and Biomedical Analysis Volume 129, 10 September 2016, Pages 558-570

Development of 2,4-Diaminopyrimidines as Antimalarials Based on Inhibition of the S108N and C59R+S108N Mutants of Dihydrofolate Reductase from Pyrimethamine-Resistant Plasmodium falciparum

Bongkoch Tarnchompoo, Chawanee Sirichaiwat, Worrapong Phupong, Chakapong Intaraudom, Worachart Sirawaraporn, Sumalee Kamchonwongpaisan, Jarunee Vanichtanankul, Yodhathai Thebtaranonth, and Yongyuth Yuthavong – J. Med. Chem. 2002, 45, 6, 1244–1252

Validated HPTLC Method for Simultaneous Analysis of Pyrimethamine and Sulphadoxine in Pharmaceutical Dosage Forms

S. Meena and S. M. Sandhya – Hindawi Publishing Corporation Journal of Chemistry Volume 2013, Article ID 698490, 6 pages

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