Raltegravir EP Impurity F

CAT No.

ALN-R009007

CAS No.

Mol. F.

C22H27FN6O6

Mol. Wt.

490.5

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Product Overview

Technical Data

Reference

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Product Overview

Chemical Name : Ethyl (1E)-N-[[2-[4-[[(4-fluorophenyl)methyl]carbamoyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl]propan-2-yl]oxamoyl]ethanehydrazonate (as per EP); Ethyl (E)-N-{2-[(2-{4-[(4-fluorobenzyl)carbamoyl]-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidin-2-yl}propan-2-yl)amino]-2-oxoacetyl}acetohydrazonate (as per USP)

Smiles : CCO/C(C)=N/NC(C(NC(C)(C)C(N1C)=NC(C(NCC2=CC=C(F)C=C2)=O)=C(O)C1=O)=O)=O

Inchi : InChI=1S/C21H25ClO7/c1-2-28-13-6-3-11(4-7-13)17(24)14-9-12(5-8-15(14)22)21-20(27)19(26)18(25)16(10-23)29-21/h3-9,16-21,23-27H,2,10H2,1H3/t16-,17?,18-,19+,20-,21+/m1/s1

Synonym : Raltegravir E-ethoxyacethydrazone analog

Technical Data

Reference

By Shirisha, V.; Sairaju, B.; Illendula, Santhosh; Dutt, K. RajeswarnFrom World Journal of Pharmacy and Pharmaceutical Sciences (2019), 8(10), 668-692

By Annapurna, Mukthinuthalapati Mathrusri; Teja, Gunnam Ravi; Hemchand, S.; Babu, R. Ravi Chandra – From International Journal of Green Pharmacy (2018), 12(1Suppl.), S177-S180

By Balaji, M.; AppaRao, K. M. Ch.; Ramakrishna, K.; Srinivasarao, V. – From Pharma Science Monitor (2014), 5(3Suppl.1), 187-196, 10 pp.

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