Ritonavir EP Impurity J

CAT No.

ALN-R003011

CAS No.

162849-95-8

Mol. F.

C28H35N3O5S

Mol. Wt.

525.7

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Product Overview

Technical Data

Reference

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Product Overview

Chemical Name : Thiazol-5-yl-methyl [(1S,2S,4S)-1-benzyl4-[[(1,1-dimethylethoxy)carbonyl] amino]-2-hydroxy-5-phenylpentyl]carbamate (as per EP); thiazol-5-ylmethyl (2S,3S,5S)-(5-t-butoxycarbonylamino)-3-hydroxy-1,6-diphenylhexan-2-ylcarbamate (as per USP)

Smiles : O[C@@H](C[C@@H](NC(OC(C)(C)C)=O)CC1=CC=CC=C1)[C@@H](NC(OCC2=CN=CS2)=O)CC3=CC=CC=C3

Inchi : InChI=1S/C36H46N6O5S2/c1-5-32-38-28(22-48-32)20-42(4)35(45)41-33(24(2)3)34(44)39-27(16-25-12-8-6-9-13-25)18-31(43)30(17-26-14-10-7-11-15-26)40-36(46)47-21-29-19-37-23-49-29/h6-15,19,22-24,27,30-31,33,43H,5,16-18,20-21H2,1-4H3,(H,39,44)(H,40,46)(H,41,45)/t27-,30-,31-,33-/m0/s1

Synonym : Ritonavir BOC-Aminoalcohol (USP)

Technical Data

Reference

By Kamalakannan, Dhanabalan; AnandaThangadurai, SubramaniamnFrom International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 611-619

By Raghu, P. S. – From World Journal of Pharmaceutical Research (2018), 7(3), 1750-1757

By Kuna, Mangamma; Dannana, Gowri Sankar – From Asian Journal of Chemistry (2018), 30(6), 1277-1283

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