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2,5-Dioxopyrrolidine Sacubitril

2,5-Dioxopyrrolidine Sacubitril

Product Description
CAT No.
ALN-S020005
CAS No.
1038924-97-8
Mol. F.
C24H27NO4
Mol. Wt.
393.5
Stock
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RFQ
Chemical Name : Ethyl (2R,4S)-5-([1,1′-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate
Smiles : C[C@@H](C(OCC)=O)C[C@H](N(C1=O)C(CC1)=O)CC2=CC=C(C3=CC=CC=C3)C=C2
Inchi : InChI=1S/C18H19NO/c1-13-11-17(19-18(13)20)12-14-7-9-16(10-8-14)15-5-3-2-4-6-15/h2-10,13,17H,11-12H2,1H3,(H,19,20)/t13-,17+/m1/s1

A liquid chromatographic method for separation of sacubitrilu2013valsartan and their stereoisomeric impurities

Lu Zhou,u00a0 Liang Zou,u00a0 Lili Sun,u00a0 Hui Zhang,u00a0 Wenkai Hui andu00a0 Qiaogen ZounAnal. Methods, 2018,10, 1046-1053

Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS

Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi – Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645

Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics

Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud – Chromatographia volume 81, pages139–156(2018)

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