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Sacubitril (3R,5S)-Pyrrolidinone Impurity

Sacubitril (3R,5S)-Pyrrolidinone Impurity

Product Description
CAT No.
ALN-S020004
CAS No.
1038924-70-7
Mol. F.
C18H19NO
Mol. Wt.
265.4
Stock
In Stock
RFQ
Chemical Name : (3R,5S)-5-([1,1′-Biphenyl]-4-ylmethyl)-3-methylpyrrolidin-2-one
Smiles : C[C@@H]1C[C@H](NC1=O)CC2=CC=C(C3=CC=CC=C3)C=C2
Inchi : InChI=1S/C24H29NO5/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28)/t17-,21-/m1/s1

A liquid chromatographic method for separation of sacubitrilu2013valsartan and their stereoisomeric impurities

Lu Zhou,u00a0 Liang Zou,u00a0 Lili Sun,u00a0 Hui Zhang,u00a0 Wenkai Hui andu00a0 Qiaogen ZounAnal. Methods, 2018,10, 1046-1053

Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS

Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi – Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645

Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics

Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud – Chromatographia volume 81, pages139–156(2018)

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