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Sacubitril Impurity 10

Sacubitril Impurity 10

Product Description
CAT No.
ALN-S020013
CAS No.
149709-60-4
Mol. F.
C25H33NO4
Mol. Wt.
411.6
Stock
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RFQ
Chemical Name : Ethyl (2R,4S)-5-([1,1′-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoate
Smiles : C[C@@H](C(OCC)=O)C[C@H](NC(OC(C)(C)C)=O)CC1=CC=C(C2=CC=CC=C2)C=C1
Inchi : InChI=1S/C20H25NO2.ClH/c1-3-23-20(22)15(2)13-19(21)14-16-9-11-18(12-10-16)17-7-5-4-6-8-17;/h4-12,15,19H,3,13-14,21H2,1-2H3;1H/t15-,19+;/m1./s1

A liquid chromatographic method for separation of sacubitrilu2013valsartan and their stereoisomeric impurities

Lu Zhou,u00a0 Liang Zou,u00a0 Lili Sun,u00a0 Hui Zhang,u00a0 Wenkai Hui andu00a0 Qiaogen ZounAnal. Methods, 2018,10, 1046-1053

Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS

Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi – Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645

Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics

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