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Sacubitril Impurity 46

Sacubitril Impurity 46

Product Description
CAT No.
ALN-S020064
CAS No.
NA
Mol. F.
C24H28N2O5
Mol. Wt.
424.5
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RFQ
Chemical Name : (2S)-2-(((2S,4R)-1-([1,1′-biphenyl]-4-yl)-4-carboxypentan-2-yl)carbamoyl)pyrrolidine-3-carboxylic acid
Smiles : O=C(O)[C@H](C)C[C@H](NC([C@H]1NCCC1C(O)=O)=O)CC2=CC=C(C3=CC=CC=C3)C=C2

A liquid chromatographic method for separation of sacubitrilu2013valsartan and their stereoisomeric impurities

Lu Zhou,u00a0 Liang Zou,u00a0 Lili Sun,u00a0 Hui Zhang,u00a0 Wenkai Hui andu00a0 Qiaogen ZounAnal. Methods, 2018,10, 1046-1053

Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS

Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi – Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645

Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics

Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud – Chromatographia volume 81, pages139–156(2018)

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