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Sacubitril Maleic Acid (E-Isomer)

Sacubitril Maleic Acid (E-Isomer)

Product Description
CAT No.
ALN-S020028
CAS No.
NA
Mol. F.
C24H27NO5
Mol. Wt.
409.5
Stock
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RFQ
Chemical Name : (E)-4-(((2S,4R)-1-([1,1′-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobut-2-enoic acid
Smiles : C[C@@H](C(OCC)=O)C[C@H](NC(/C=C/C(O)=O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1
Inchi : InChI=1S/C12H7ClN6/c13-9-7-2-4-19(11(7)17-5-15-9)12-8-1-3-14-10(8)16-6-18-12/h1-6H,(H,14,16,18)

A liquid chromatographic method for separation of sacubitrilu2013valsartan and their stereoisomeric impurities

Lu Zhou,u00a0 Liang Zou,u00a0 Lili Sun,u00a0 Hui Zhang,u00a0 Wenkai Hui andu00a0 Qiaogen ZounAnal. Methods, 2018,10, 1046-1053

Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS

Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi – Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645

Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics

Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud – Chromatographia volume 81, pages139–156(2018)

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