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Sacubitril Maleic Acid (Z-Isomer)

Sacubitril Maleic Acid (Z-Isomer)

Product Description
CAT No.
ALN-S020059
CAS No.
2751722-77-5
Mol. F.
C24H27NO5
Mol. Wt.
409.5
Stock
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RFQ
Chemical Name : (Z)-4-(((2S,4R)-1-([1,1′-biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobut-2-enoic acid
Smiles : O=C(O)/C=C\C(N[C@@H](C[C@@H](C)C(OCC)=O)CC1=CC=C(C2=CC=CC=C2)C=C1)=O
Inchi : InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)

A liquid chromatographic method for separation of sacubitrilu2013valsartan and their stereoisomeric impurities

Lu Zhou,u00a0 Liang Zou,u00a0 Lili Sun,u00a0 Hui Zhang,u00a0 Wenkai Hui andu00a0 Qiaogen ZounAnal. Methods, 2018,10, 1046-1053

Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS

Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi – Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645

Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics

Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud – Chromatographia volume 81, pages139–156(2018)

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