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Sacubitril Sodium

Sacubitril Sodium

Product Description
CAT No.
ALN-S020040
CAS No.
149690-05-1
Mol. F.
C24H29NO5 : Na
Mol. Wt.
411.5 : 23.0
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RFQ
Chemical Name : 4-(((2S,4R)-1-([1,1′-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid, sodium salt
Smiles : C[C@@H](C(OCC)=O)C[C@H](NC(CCC(O)=O)=O)CC1=CC=C(C2=CC=CC=C2)C=C1.[Na]
Inchi : InChI=1S/C32H44NO8.C6H6O3S/c1-7-31(34)40-17-9-8-10-18-41-32(35)14-16-33(2)15-13-24-21-29(38-5)30(39-6)22-25(24)26(33)19-23-11-12-27(36-3)28(20-23)37-4;7-10(8,9)6-4-2-1-3-5-6/h7,11-12,20-22,26H,1,8-10,13-19H2,2-6H3;1-5H,(H,7,8,9)/q+1;/p-1/t26-,33-;/m0./s1

A liquid chromatographic method for separation of sacubitrilu2013valsartan and their stereoisomeric impurities

Lu Zhou,u00a0 Liang Zou,u00a0 Lili Sun,u00a0 Hui Zhang,u00a0 Wenkai Hui andu00a0 Qiaogen ZounAnal. Methods, 2018,10, 1046-1053

Quantification of potential genotoxic impurity in sacubitril/valsartan drug substance at ppm level by LC-MS/MS

Ravi Uppala, M.Arthanareeswari, S.Devikala,T.Pushpamalini, J. ArockiaSelvi – Materials Today: Proceedings Volume 14, Part 2, 2019, Pages 640-645

Experimental Design Approach in HPLC Method Development: Application for the Simultaneous Determination of Sacubitril and Valsartan in Presence of Their Impurities and Investigation of Degradation Kinetics

Bahia A. Moussa, Hanaa M. A. Hashem, Marianne A. Mahrouse & Sally T. Mahmoud – Chromatographia volume 81, pages139–156(2018)

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