RP-Isomer of Sofosbuvir

CAT No.

ALN-S010005

CAS No.

1190308-01-0

Mol. F.

C22H29FN3O9P

Mol. Wt.

529.5

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Product Overview

Technical Data

Reference

RFQ

Product Overview

Chemical Name : Isopropyl ((R)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate

Smiles : O[C@@H]1[C@@H](CO[P@@](OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)O[C@@H](N3C(NC(C=C3)=O)=O)[C@]1(C)F

Inchi : InChI=1S/C16H25FN3O9P/c1-8(2)28-13(23)9(3)19-30(25,26)27-7-10-12(22)16(4,17)14(29-10)20-6-5-11(21)18-15(20)24/h5-6,8-10,12,14,22H,7H2,1-4H3,(H,18,21,24)(H2,19,25,26)/t9-,10+,12+,14+,16+/m0/s1

Technical Data

Reference

By Suma, M. S. M.; Gowthami, M.; Latha, P. V. Madhavi; Devi, P. UmanFrom Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9037-9043.

By Prabhaker, Naik Desai Prabhat; Pankaj, Kapupara – From International Journal of Research in Pharmaceutical Sciences (Madurai, India) (2021), 12(1), 523-529.

By El-Yazbi, Amira F.; Elashkar, Nourhan E.; Abdel-Hay, Karim M.; Talaat, Wael; Ahmed, Hytham M. – From Microchemical Journal (2020), 154, 104584.

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