Sunitinib Impurity 10

Product Description
CAT No.
ALN-S016030
CAS No.
2377533-90-7
Mol. F.
C22H27FN4O3
Mol. Wt.
414.5
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Product Overview
Technical Data
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Product Overview
Chemical Name : (Z)-N-(2-(Diethylamino)ethyl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2-(hydroxymethyl)-4-methyl-1H-pyrrole-3-carboxamide
Smiles : O=C(C1=C(CO)NC(/C=C2C(NC3=C\2C=C(F)C=C3)=O)=C1C)NCCN(CC)CC
Inchi : InChI=1S/C23H26N6O/c1-4-5-10-20-24-23(2,3)22(30)29(20)15-16-11-13-17(14-12-16)18-8-6-7-9-19(18)21-25-27-28-26-21/h6-9,11-14H,4-5,10,15H2,1-3H3,(H,25,26,27,28)
Technical Data
Reference
Physicochemical characteristics of sunitinib malate and its process-related impurities
Katarzyna Sidoryk 1, Maura Maliu0144ska, Krzysztof Bau0144kowski, Marek Kubiszewski, Marta u0141aszcz, Magdalena Bodziachowska-Panfil, Magdalena Kossykowska, Tomasz Giller, Andrzej Kutner, Krzysztof Wou017aniaknJ Pharm Sci. 2013 Feb;102(2):706-16.
Development and validation of a HPTLC method for analysis of Sunitinib malate
Monireh Hajmalek, Masoumeh Goudarzi , Solmaz Ghaffari,Hossein Attar, Mehrnoosh Ghanbari Mazlaghan – Brazilian Journal of Pharmaceutical Sciences vol. 52, n. 4, oct./dec., 2016
Reverse phase HPLC determination of sunitinib malate using UV detector, its isomerisation study, method development and validation
Mohsen Padervand, Solmaz Ghaffari, Hossein Attar & Mahdieh Mohammad Nejad – Journal of Analytical Chemistry volume 72, pages567–574(2017)
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