Sunitinib Impurity 8
 
		Product Description
CAT No.
				
									ALN-S016026								
				CAS No.
				
									NA								
				Mol. F.
				
									C16H17FN2O4								
				Mol. Wt.
				
									320.3								
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									Chemical Name : (2Z,4E)-2-(2-Amino-5-fluorophenyl)-4-(((E)-1-carboxyprop-1-en-2-yl)amino)hexa-2,4-dienoic acid								
				
									Smiles : FC1=CC=C(N)C(/C(C(O)=O)=C/C(N/C(C)=C/C(O)=O)=C\C)=C1								
				
									Inchi : InChI=1S/C22H31FN4O3/c1-5-17(14-19(22(29)30)18-13-16(23)8-9-20(18)24)26-15(4)12-21(28)25-10-11-27(6-2)7-3/h5,8-9,12-14,26H,6-7,10-11,24H2,1-4H3,(H,25,28)(H,29,30)/b15-12+,17-5+,19-14-								
				
							
							
							Technical Data
			
						
							
							
							Reference
			
						Physicochemical characteristics of sunitinib malate and its process-related impurities
									Katarzyna Sidoryk 1, Maura Maliu0144ska, Krzysztof Bau0144kowski, Marek Kubiszewski, Marta u0141aszcz, Magdalena Bodziachowska-Panfil, Magdalena Kossykowska, Tomasz Giller, Andrzej Kutner, Krzysztof Wou017aniaknJ Pharm Sci. 2013 Feb;102(2):706-16.								
				Development and validation of a HPTLC method for analysis of Sunitinib malate
									Monireh Hajmalek, Masoumeh Goudarzi , Solmaz Ghaffari,Hossein Attar, Mehrnoosh Ghanbari Mazlaghan – Brazilian Journal of Pharmaceutical Sciences vol. 52, n. 4, oct./dec., 2016 								
				Reverse phase HPLC determination of sunitinib malate using UV detector, its isomerisation study, method development and validation
									Mohsen Padervand, Solmaz Ghaffari, Hossein Attar & Mahdieh Mohammad Nejad – Journal of Analytical Chemistry volume 72, pages567–574(2017)								
				
							
							
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