Teriflunomide Impurity 31

Product Description
CAT No.
ALN-T015037
CAS No.
16045-84-4
Mol. F.
C29H22F6N4O2
Mol. Wt.
572.5
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 1,1′-(Methylenebis(4,1-phenylene))bis(3-(3-(trifluoromethyl)phenyl)urea)
Smiles : O=C(NC1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(CC3=CC=C(NC(NC4=CC=CC(C(F)(F)F)=C4)=O)C=C3)C=C2
Inchi : InChI=1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1/i11+1D3
Technical Data
Reference
Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application to in-vitro dissolution
Nukendra Prasad Nadella,Venkata Nadh Ratnakaram & N. SrinivasunJournal of Liquid Chromatography & Related Technologies Volume 40, 2017 – Issue 10 Pages 517-527
Development of Validated Stability Indicating HPTLC Method for the Estimation of Teriflunomide in Bulk and Tablet Dosage Form
Karmankar, Snehal; Tajne, M. – Current Pharmaceutical Analysis, Volume 16, Number 7, 2020, pp. 814-822(9)
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