Vildagliptin Impurity 18

Product Description
CAT No.
ALN-V008048
CAS No.
2380224-94-0
Mol. F.
C20H29N3O4S
Mol. Wt.
407.5
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 2-((S)-1-(((1r,3R,5R,7S)-3-Hydroxyadamantan-1-yl)glycyl)pyrrolidin-2-yl)-4,5-dihydrothiazole-4-carboxylic acid
Smiles : O=C(N1[C@H](C2=NC(C(O)=O)CS2)CCC1)CN[C@](C[C@H](C3)C4)(C[C@@H]3C5)C[C@]45O
Inchi : InChI=1/C21H22N9O8PS4/c1-3-38-25-14(16-24-20(43-27-16)26-39(35,36)37)17(31)23-15(19(32)33)18-30(28-34)8-12(9-40-18)42-21-22-13(10-41-21)11-4-6-29(2)7-5-11/h4-8,10,15,18H,3,9H2,1-2H3,(H4-,23,24,26,27,31,32,33,35,36,37)/b25-14-
Technical Data
Reference
Identification, isolation and characterization of potential process-related impurity and its degradation product in vildagliptin
Neeraj Kumar, Subba Rao Devineni, Gurmeet Singh, A.Kadirappa, Shailendra Kumar, Dubey, Pramod KumarnJournal of Pharmaceutical and Biomedical Analysis Volume 119, 5 February 2016, Pages 114-121
Development and validation of a cyclodextrinu2010modified capillary electrophoresis method for the enantiomeric separation of vildagliptin enantiomers
Adrienn Kazsoki\xa0 Ida Fej?s\xa0 Tamás Sohajda\xa0 Wei Zhou\xa0 Wenhui Hu\xa0 Lajos Szente\xa0 Szabolcs Béni – Electrophoresis Volume37, Issue10 May 2016 Pages 1318-1325
New forced degradation products of vildagliptin: Identification and structural elucidation using LC-MS, with proposed formation mechanisms
Sharif Arar,Enas Al-Qudah,Muhammad Alzweiri &Kamal Sweidan – Journal of Liquid Chromatography & Related Technologies\xa0 Volume 43, 2020 – Issue 15-16 Pages 633-644
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