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Vildagliptin Nitroso Impurity 1

Vildagliptin Nitroso Impurity 1

Product Description
CAT No.
ALN-V008052
CAS No.
NA
Mol. F.
C17H24N4O3
Mol. Wt.
332.4
Stock
Under Synthesis
Chemical Name : N-(2-((S)-2-Cyanopyrrolidin-1-yl)-2-oxoethyl)-N-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)nitrous amide
Smiles : O=C(N(CCC1)[C@@H]1C#N)CN(N=O)[C@](C[C@H](C2)C3)(C[C@@H]2C4)C[C@]34O
Inchi : InChI=1/C6H10Cl2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4H2,(H,9,10)

Identification, isolation and characterization of potential process-related impurity and its degradation product in vildagliptin

Neeraj Kumar, Subba Rao Devineni, Gurmeet Singh, A.Kadirappa, Shailendra Kumar, Dubey, Pramod KumarnJournal of Pharmaceutical and Biomedical Analysis Volume 119, 5 February 2016, Pages 114-121

Development and validation of a cyclodextrinu2010modified capillary electrophoresis method for the enantiomeric separation of vildagliptin enantiomers

Adrienn Kazsoki\xa0 Ida Fej?s\xa0 Tamás Sohajda\xa0 Wei Zhou\xa0 Wenhui Hu\xa0 Lajos Szente\xa0 Szabolcs Béni – Electrophoresis Volume37, Issue10 May 2016 Pages 1318-1325

New forced degradation products of vildagliptin: Identification and structural elucidation using LC-MS, with proposed formation mechanisms

Sharif Arar,Enas Al-Qudah,Muhammad Alzweiri &Kamal Sweidan – Journal of Liquid Chromatography & Related Technologies\xa0 Volume 43, 2020 – Issue 15-16 Pages 633-644

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