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Abemaciclib Metabolites M2

Abemaciclib Metabolites M2

Product Description
CAT No.
ALN-A077004
CAS No.
1231930-57-6
Mol. F.
C25H28F2N8
Mol. Wt.
478.6
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RFQ
Chemical Name : 5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-(5-(piperazin-1-ylmethyl)pyridin-2-yl)pyrimidin-2-amine
Smiles : CC(N1C2=CC(C3=NC(NC4=CC=C(CN5CCNCC5)C=N4)=NC=C3F)=CC(F)=C2N=C1C)C

Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry

By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.nFrom Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345

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