N-Nitroso Apalutamide Impurity 3

Product Description
CAT No.
ALN-A086031
CAS No.
NA
Mol. F.
C13H14FN3O4
Mol. Wt.
295.3
Stock
In Stock
Product Overview
Technical Data
Reference
RFQ
Product Overview
Chemical Name : 1-((3-Fluoro-4-(methylcarbamoyl)phenyl)(nitroso)amino)cyclobutane-1-carboxylic acid
Smiles : O=C(C1(N(C2=CC=C(C(NC)=O)C(F)=C2)N=O)CCC1)O
Technical Data
Reference
Structure-Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for Castration-Resistant Prostate Cancer (CRPC)
Michael E. Jung,*,u2020 Samedy Ouk,u2020 Dongwon Yoo,u2020 Charles L. Sawyers,u2021,u00a7 Charlie Chen,u2021 Chris Tran,u2021 and John WongvipatnJ. Med. Chem. 2010, 53, 2779u20132796
Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide
,† Samedy Ouk,† Dongwon Yoo,† Charles L. Sawyers,‡,§ Charlie Chen,‡ Chris Tran,‡ and John Wongvipat – J. Med. Chem. 2010, 53, 2779–2796
Discovery of deshydroxy bicalutamide derivatives as androgen receptor antagonists
David L. Hughes – Org. Process Res. Dev. 2020, 24, 3, 347–362
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