Cefaclor EP Impurity E
Product Description
CAT No.
ALN-C067006
CAS No.
188915-50-6
Mol. F.
C14H14ClN3O4S
Mol. Wt.
355.8
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Product Overview
Technical Data
Reference
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Product Overview
Chemical Name : 2-[[(2R)-2-Amino-2-phenylacetyl]amino]-2-(5-chloro-4-oxo-3,4-dihydro-2H-1,3-thiazin-2-yl)acetic acid (as per EP)
Smiles : O=C(O)C(NC([C@H](N)C1=CC=CC=C1)=O)C(N2)SC=C(Cl)C2=O
Inchi : InChI=1S/C15H14ClN3O4S/c16-8-6-24-14-10(13(21)19(14)11(8)15(22)23)18-12(20)9(17)7-4-2-1-3-5-7/h1-6,9-11,14H,17H2,(H,18,20)(H,22,23)/t9-,10-,11?,14-/m1/s1
Synonym : Cefaclor Open-Ring Impurity
Technical Data
Reference
Multidimensional evaluation of impurity profiles for generic cephalexin and cefaclor antibiotics
B.A. Olsen*, S.W. Baertschi and R.M. RigginnJournal of Chromatography, 648 (1993) 165-173
Mass Spectral Profile for Rapid Differentiating Beta-Lactams from Their Ring-Opened Impurities
, S.W. Baertschi and R.M. Riggin – Journal of Chromatography, 648 (1993) 165-173
The Degradation Mechanism of an Oral Cephalosporin: Cefaclor
Hecheng Wang,1,2 Haiwei Huang,3 Jin Cao,3 Dehua Chui,2 and Shengyuan Xiao – Hindawi Publishing Corporation BioMed Research International Volume 2015, Article ID 697958, 13 pages
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