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Enzalutamide Impurity 43

Enzalutamide Impurity 43

Product Description
CAT No.
ALN-E015062
CAS No.
NA
Mol. F.
C16H16F2N4O2
Mol. Wt.
334.3
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RFQ
Chemical Name : 4,4′-(hydrazine-1,2-diyl)bis(2-fluoro-N-methylbenzamide)
Smiles : O=C(NC)C1=CC=C(NNC2=CC=C(C(F)=C2)C(NC)=O)C=C1F
Inchi : InChI=1S/C20H17Cl3N2O2/c21-3-1-11-6-14-8-20(27)25(18(14)10-16(11)23)4-2-12-5-13-7-19(26)24-17(13)9-15(12)22/h5-6,9-10H,1-4,7-8H2,(H,24,26)

Structural elucidation of the impurities in Enzalutamide bulk drug and the development, validation of corresponding HPLC method

Xingling Mab , Wentao Zhoua , Qiaogen Zoua,*, Pingkai OuyangnJournal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Crystal Forms of Enzalutamide and a Crystal Engineering Route to Drug Purification

, Pingkai Ouyang – Journal of Pharmaceutical and Biomedical Analysis Volume 131, 30 November 2016, Pages 436-443

Quantitative Study of\xa0Impurities in\xa0Enzalutamide and\xa0Identification, Isolation, Characterization of\xa0Its Four Degradation Products Using HPLC, Semi-preparative LC, LC/ESI–MS and\xa0NMR Analyses

Lucia Maini, Dario Braga, Francesco Farinella, Elisa Melotto, Massimo Verzini, Roberto Brescello, Ivan Michieletto, and Ilaria Munari – Cryst. Growth Des. 2018, 18, 7, 3774–3780

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