​2-​Methanol Abemaciclib

Product Description
CAT No.
ALN-A077009
CAS No.
2138499-06-4
Mol. F.
C27H32F2N8O
Mol. Wt.
522.6
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Technical Data
Reference
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Product Overview
Chemical Name : (6-(2-((5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-yl)amino)-5-fluoropyrimidin-4-yl)-4-fluoro-1-isopropyl-1H-benzo[d]imidazol-2-yl)methanol
Smiles : CC(N1C2=CC(C3=NC(NC(N=C4)=CC=C4CN(CC5)CCN5CC)=NC=C3F)=CC(F)=C2N=C1CO)C
Technical Data
Reference
Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry
By Martinez-Chavez, Alejandra; Rosing, Hilde; Hillebrand, Michel; Tibben, Matthijs; Schinkel, Alfred H.; Beijnen, Jos H.nFrom Analytical and Bioanalytical Chemistry (2019), 411(20), 5331-5345
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