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Apalutamide Impurity 10

Apalutamide Impurity 10

Product Description
CAT No.
ALN-A086021
CAS No.
573762-62-6
Mol. F.
C7H4F3N3
Mol. Wt.
187.1
Stock
In Stock
Chemical Name : 5-Amino-3-(trifluoromethyl)picolinonitrile
Smiles : FC(F)(C(C=C(N)C=N1)=C1C#N)F

Structure-Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for Castration-Resistant Prostate Cancer (CRPC)

Michael E. Jung,*,u2020 Samedy Ouk,u2020 Dongwon Yoo,u2020 Charles L. Sawyers,u2021,u00a7 Charlie Chen,u2021 Chris Tran,u2021 and John WongvipatnJ. Med. Chem. 2010, 53, 2779u20132796

Review of Synthetic Routes and Crystalline Forms of the Antiandrogen Oncology Drugs Enzalutamide, Apalutamide, and Darolutamide

,† Samedy Ouk,† Dongwon Yoo,† Charles L. Sawyers,‡,§ Charlie Chen,‡ Chris Tran,‡ and John Wongvipat – J. Med. Chem. 2010, 53, 2779–2796

Discovery of deshydroxy bicalutamide derivatives as androgen receptor antagonists

David L. Hughes – Org. Process Res. Dev. 2020, 24, 3, 347–362

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