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Quetiapine EP Impurity B (Fumarate salt)

Quetiapine EP Impurity B (Fumarate salt)

Product Description
CAT No.
ALN-Q001068
CAS No.
937731-18-5
Mol. F.
C17H17N3S : C4H4O4
Mol. Wt.
295.4 : 116.1
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RFQ
Chemical Name : 11-(piperazin-1-yl)dibenzo[b,f][1,4]thiazepine fumarate (as per EP & USP)
Smiles : OC(/C=C/C(O)=O)=O.C1(N2CCNCC2)=NC3=CC=CC=C3SC4=CC=CC=C14
Inchi : InChI=1S/C11H18N2O/c1-2-3-6-9-12-10(14)11(13-9)7-4-5-8-11/h2-8H2,1H3,(H,12,13,14)
Synonym : Quetiapine USP Related Compound B ; N-Desalkyl Quetiapine

Identification and Characterization of Potential Impurities of Quetiapine Fumarate

Elu017cbieta U. Stolarczyk,u0141ukasz Kaczmarek,Kamil Eksanow,Marek Kubiszewski,Magdalena Glice &Andrzej KutnernPharmaceutical Development and Technologyu00a0 Volume 14, 2009 – Issue 1 Pages 29-39

An Improved and Single Pot Process for the Production of Quetiapine Hemifumarate Substantially Free from Potential Impurities

Navnath C. Niphade, Anil C. Mali, Bhushan S. Pandit, Kunal M. Jagtap, Sanjay A. Jadhav, Madhukar N. Jachak, and Vijayavitthal T. Mathad – Org. Process Res. Dev. 2009, 13, 4, 792–797

Stability indicating fast LC method for determination of quetiapine fumarate related substances in bulk and pharmaceutical formulation

R.Narendra Kumar,

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